Path ID: DB00734_MESH_D012559_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D018967 | risperidone | Drug |
| UniProt:P14416 | D(2) dopamine receptor | Protein |
| UniProt:P28223 | 5-hydroxytryptamine receptor 2A | Protein |
| GO:0061527 | dopamine secretion, neurotransmission | BiologicalProcess |
| GO:0060096 | serotonin secretion, neurotransmission | BiologicalProcess |
| HP:0000738 | Hallucinations | PhenotypicFeature |
| MESH:D012701 | Serotonin | ChemicalSubstance |
| MESH:D012559 | Schizophrenia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Risperidone | DECREASES ACTIVITY OF | D(2) Dopamine Receptor |
| Risperidone | DECREASES ACTIVITY OF | 5-Hydroxytryptamine Receptor 2A |
| D(2) Dopamine Receptor | PARTICIPATES IN | Dopamine Secretion, Neurotransmission |
| 5-Hydroxytryptamine Receptor 2A | PARTICIPATES IN | Serotonin Secretion, Neurotransmission |
| Dopamine Secretion, Neurotransmission | POSITIVELY REGULATES | Hallucinations |
| Serotonin Secretion, Neurotransmission | POSITIVELY CORRELATED WITH | Serotonin |
| Hallucinations | MANIFESTATION OF | Schizophrenia |
| Serotonin | POSITIVELY CORRELATED WITH | Schizophrenia |
Reference: