Path ID: DB00687_MESH_D000312_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C034635 | Fludrocortisone acetate | Drug |
| MESH:D005438 | Fludrocortisone | ChemicalSubstance |
| UniProt:P08235 | Mineralocorticoid receptor | Protein |
| MESH:D000450 | Aldosterone | ChemicalSubstance |
| MESH:D000312 | Congenital adrenal hyperplasia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fludrocortisone Acetate | HAS METABOLITE | Fludrocortisone |
| Fludrocortisone | INCREASES ACTIVITY OF | Mineralocorticoid Receptor |
| Mineralocorticoid Receptor | POSITIVELY CORRELATED WITH | Aldosterone |
| Aldosterone | NEGATIVELY CORRELATED WITH | Congenital Adrenal Hyperplasia |
Comment: Fludrocortisone acetate is a prodrug of fludrocortisone, a synthetic mineralocorticoid used in conjunction with hydrocortisone
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