Path ID: DB00678_MESH_D003928_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D019808 | Losartan | Drug |
| UniProt:P30556 | Type-1 angiotensin II receptor | Protein |
| MESH:D000804 | Angiotensin II | ChemicalSubstance |
| MESH:D014661 | Vasoconstriction | Disease |
| HP:0000822 | Hypertension | PhenotypicFeature |
| MESH:D003928 | Diabetic renal disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Losartan | NEGATIVELY REGULATES | Type-1 Angiotensin Ii Receptor |
| Type-1 Angiotensin Ii Receptor | POSITIVELY CORRELATED WITH | Angiotensin Ii |
| Angiotensin Ii | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | POSITIVELY CORRELATED WITH | Hypertension |
| Hypertension | AFFECTS RISK FOR | Diabetic Renal Disease |
Reference: