Path ID: DB00668_MESH_D007022_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D004837 | epinephrine | Drug |
| UniProt:P08588 | Beta-1 adrenergic receptor | Protein |
| reactome:R-HSA-418555 | G alpha (s) signalling events | Pathway |
| GO:0060047 | heart contraction | BiologicalProcess |
| HP:0033533 | Increased cardiac output | PhenotypicFeature |
| MESH:D007022 | Low blood pressure | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Epinephrine | INCREASES ACTIVITY OF | Beta-1 Adrenergic Receptor |
| Beta-1 Adrenergic Receptor | PARTICIPATES IN | G Alpha (S) Signalling Events |
| G Alpha (S) Signalling Events | POSITIVELY REGULATES | Heart Contraction |
| Heart Contraction | POSITIVELY CORRELATED WITH | Increased Cardiac Output |
| Increased Cardiac Output | NEGATIVELY CORRELATED WITH | Low Blood Pressure |
Reference: