Path ID: DB00645_MESH_D011537_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C100063 | dyclonine | Drug |
| InterPro:IPR001696 | Voltage gated sodium channel, alpha subunit | GeneFamily |
| GO:0005248 | Voltage-gated sodium channel activity | BiologicalProcess |
| GO:0051899 | Membrane depolarization | BiologicalProcess |
| GO:0019228 | neuronal action potential | BiologicalProcess |
| GO:0050806 | positive regulation of synaptic transmission | BiologicalProcess |
| GO:1904058 | positive regulation of sensory perception of pain | BiologicalProcess |
| CL:0000197 | Sensory Receptor Cell | Cell |
| MESH:D011537 | Itching of skin | Drug |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Dyclonine | DECREASES ACTIVITY OF | Voltage Gated Sodium Channel, Alpha Subunit |
| Voltage Gated Sodium Channel, Alpha Subunit | PARTICIPATES IN | Voltage-Gated Sodium Channel Activity |
| Voltage-Gated Sodium Channel Activity | POSITIVELY REGULATES | Membrane Depolarization |
| Membrane Depolarization | POSITIVELY REGULATES | Neuronal Action Potential |
| Neuronal Action Potential | CONTRIBUTES TO | Positive Regulation Of Synaptic Transmission |
| Positive Regulation Of Synaptic Transmission | ACTIVELY INVOLVED IN | Positive Regulation Of Sensory Perception Of Pain |
| Positive Regulation Of Sensory Perception Of Pain | POSITIVELY REGULATES | Sensory Receptor Cell |
| Sensory Receptor Cell | POSITIVELY CORRELATED WITH | Itching Of Skin |
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