Path ID: DB00637_MESH_D012912_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D016589 | Astemizole | Drug |
| UniProt:P35367 | Histamine H1 receptor | Protein |
| GO:0051381 | Histamine binding | MolecularActivity |
| GO:0023041 | Neuronal signal transduction | BiologicalProcess |
| UBERON:0000004 | Nose | GrossAnatomicalStructure |
| UBERON:0001645 | Trigeminal nerve | GrossAnatomicalStructure |
| MESH:D012912 | Sneezing | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Astemizole | DECREASES ACTIVITY OF | Histamine H1 Receptor |
| Histamine H1 Receptor | PARTICIPATES IN | Histamine Binding |
| Histamine Binding | POSITIVELY REGULATES | Neuronal Signal Transduction |
| Neuronal Signal Transduction | LOCATED IN | Nose |
| Nose | AFFECTED BY | Trigeminal Nerve |
| Trigeminal Nerve | CONTRIBUTES TO | Sneezing |
Reference: