Path ID: DB00634_MESH_D000562_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D013409 | sulfacetamide | Drug |
| GO:0006954 | inflammatory response | BiologicalProcess |
| MESH:D000562 | Amebic infection | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Sulfacetamide | NEGATIVELY REGULATES | Inflammatory Response |
| Inflammatory Response | CAUSED BY | Amebic Infection |
Comment: There seems to be no evidence linking sulfacetamide as treatment for Amebic infection. Sulfacetamide is an antibacterial type of drug (https://www.kegg.jp/entry/D05947) and it seems the drug has some anti-inflammatory role. Since the disease could lead to inflammation and ulceration of the colon perhaps there could be an anti-inflammation hypothesis but the drug is mainly available as eye drops and lotions (https://en.wikipedia.org/wiki/Sulfacetamide#Available_forms), and therefore unavailable to treat the intestinal tract in such formats. Note there are few amoeba species that may cause skin or eye issues (https://en.wikipedia.org/wiki/Acanthamoeba_keratitis), in which case sulfacetamide could potentially be an indication, albeit no evidence to prove this assumption has been found in databases or literature.
Reference: