Path ID: DB00619_MESH_D034721_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068877 | imatinib | Drug |
| UniProt:P10721 | c-Kit | Protein |
| UniProt:P16234 | Pdgf | Protein |
| GO:0008283 | Cellular proliferation | BiologicalProcess |
| MESH:D034721 | Systemic mast cell disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Imatinib | DECREASES ACTIVITY OF | C-Kit |
| Imatinib | DECREASES ACTIVITY OF | Pdgf |
| C-Kit | POSITIVELY REGULATES | Cellular Proliferation |
| Pdgf | POSITIVELY REGULATES | Cellular Proliferation |
| Cellular Proliferation | CAUSES | Systemic Mast Cell Disease |
Reference: