Path ID: DB00619_MESH_D001752_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068877 | imatinib | Drug |
| MESH:D016044 | Fusion Proteins, bcr-abl | Protein |
| GO:0007266 | Rho protein signal transduction | BiologicalProcess |
| GO:0008283 | cell population proliferation | BiologicalProcess |
| HP:0001974 | Leukocytosis | PhenotypicFeature |
| MESH:D001752 | Blast Crisis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Imatinib | DECREASES ACTIVITY OF | Fusion Proteins, Bcr-Abl |
| Fusion Proteins, Bcr-Abl | POSITIVELY CORRELATED WITH | Rho Protein Signal Transduction |
| Rho Protein Signal Transduction | POSITIVELY CORRELATED WITH | Cell Population Proliferation |
| Cell Population Proliferation | POSITIVELY CORRELATED WITH | Leukocytosis |
| Leukocytosis | MANIFESTATION OF | Blast Crisis |
Reference: