Path ID: DB00609_MESH_D014397_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D005000 | Ethionamide | Drug |
| UniProt:P9WGR1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | Protein |
| GO:0071768 | Mycolic acid biosynthetic process | BiologicalProcess |
| GO:0042546 | Cell wall biogenesis | BiologicalProcess |
| GO:0005618 | Cell wall | CellularComponent |
| taxonomy:1773 | Mycobacterium tuberculosis | OrganismTaxon |
| MESH:D014397 | Pulmonary tuberculosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ethionamide | DECREASES ACTIVITY OF | Enoyl-[Acyl-Carrier-Protein] Reductase [Nadh] |
| Enoyl-[Acyl-Carrier-Protein] Reductase [Nadh] | POSITIVELY REGULATES | Mycolic Acid Biosynthetic Process |
| Mycolic Acid Biosynthetic Process | POSITIVELY CORRELATED WITH | Cell Wall Biogenesis |
| Cell Wall Biogenesis | HAS OUTPUT | Cell Wall |
| Cell Wall | IN TAXON | Mycobacterium Tuberculosis |
| Mycobacterium Tuberculosis | CAUSES | Pulmonary Tuberculosis |
Reference: