Path ID: DB00607_MESH_D011023_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009254 | nafcillin | Drug |
| UniProt:Q8DR59 | Penicillin-binding protein 1A | Protein |
| GO:0071972 | peptidoglycan L,D-transpeptidase activity | MolecularActivity |
| GO:0018104 | peptidoglycan-protein cross-linking | BiologicalProcess |
| GO:0031504 | peptidoglycan-based cell wall organization | BiologicalProcess |
| taxonomy:1279 | Staphylococcus | OrganismTaxon |
| MESH:D011023 | Staphylococcal pneumonia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Nafcillin | NEGATIVELY REGULATES | Penicillin-Binding Protein 1A |
| Penicillin-Binding Protein 1A | POSITIVELY REGULATES | Peptidoglycan L,D-Transpeptidase Activity |
| Peptidoglycan L,D-Transpeptidase Activity | PARTICIPATES IN | Peptidoglycan-Protein Cross-Linking |
| Peptidoglycan-Protein Cross-Linking | CORRELATED WITH | Peptidoglycan-Based Cell Wall Organization |
| Peptidoglycan-Based Cell Wall Organization | IN TAXON | Staphylococcus |
| Staphylococcus | CAUSES | Staphylococcal Pneumonia |
Reference: