Path ID: DB00593_MESH_D004832_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D005013 | Ethosuximide | Drug |
| UniProt:O43497 | Voltage-dependent T-type calcium channel subunit alpha-1G | Protein |
| GO:0019228 | neuronal action potential | BiologicalProcess |
| GO:0035249 | synaptic transmission, glutamatergic | BiologicalProcess |
| MESH:D004832 | Epilepsy, Absence | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ethosuximide | DECREASES ACTIVITY OF | Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1G |
| Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1G | POSITIVELY REGULATES | Neuronal Action Potential |
| Neuronal Action Potential | CONTRIBUTES TO | Synaptic Transmission, Glutamatergic |
| Synaptic Transmission, Glutamatergic | POSITIVELY CORRELATED WITH | Epilepsy, Absence |
Reference: