Path ID: DB00589_MESH_D000172_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D008090 | Lisuride | Drug |
| UniProt:P14416 | D2 dopamine receptor | Protein |
| GO:0007195 | Adenylate cyclase-inhibiting dopamine receptor signaling pathway | BiologicalProcess |
| GO:0030252 | Growth hormone secretion | BiologicalProcess |
| MESH:D013006 | Growth Hormone | ChemicalSubstance |
| MESH:D000172 | Acromegaly | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lisuride | INCREASES ACTIVITY OF | D2 Dopamine Receptor |
| D2 Dopamine Receptor | PARTICIPATES IN | Adenylate Cyclase-Inhibiting Dopamine Receptor Signaling Pathway |
| Adenylate Cyclase-Inhibiting Dopamine Receptor Signaling Pathway | NEGATIVELY REGULATES | Growth Hormone Secretion |
| Growth Hormone Secretion | INCREASES ABUNDANCE OF | Growth Hormone |
| Growth Hormone | CAUSES | Acromegaly |
Reference: