Path ID: DB00588_MESH_D001991_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068298 | fluticasone propionate | Drug |
| UniProt:P04150 | Glucocorticoid receptor | Protein |
| UniProt:P47712 | Phospholipase A2 | Protein |
| UniProt:P22301 | IL-10 | Protein |
| GO:0006954 | Inflammation | BiologicalProcess |
| MESH:D001991 | Bronchitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fluticasone Propionate | INCREASES ACTIVITY OF | Glucocorticoid Receptor |
| Glucocorticoid Receptor | DECREASES ABUNDANCE OF | Phospholipase A2 |
| Glucocorticoid Receptor | INCREASES ABUNDANCE OF | Il-10 |
| Phospholipase A2 | POSITIVELY REGULATES | Inflammation |
| Il-10 | NEGATIVELY REGULATES | Inflammation |
| Inflammation | CAUSES | Bronchitis |
Reference: