Path ID: DB00577_MESH_D006558_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C084555 | valaciclovir | Drug |
| MESH:D000212 | Acyclovir | Drug |
| Pfam:PF11590 | DNA polymerase catalytic subunit Pol | GeneFamily |
| GO:0039693 | viral DNA genome replication | BiologicalProcess |
| taxonomy:10310 | Human alphaherpesvirus 2 | OrganismTaxon |
| MESH:D006558 | Genital herpes simplex | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Valaciclovir | HAS METABOLITE | Acyclovir |
| Acyclovir | NEGATIVELY REGULATES | Dna Polymerase Catalytic Subunit Pol |
| Dna Polymerase Catalytic Subunit Pol | POSITIVELY REGULATES | Viral Dna Genome Replication |
| Viral Dna Genome Replication | IN TAXON | Human Alphaherpesvirus 2 |
| Human Alphaherpesvirus 2 | CAUSES | Genital Herpes Simplex |
Reference: