Path ID: DB00571_MESH_D002312_1

db00571-mesh-d002312-1

Concepts

Identifier Name Type
MESH:D011433 Propranolol Drug
UniProt:P08588 Beta-1 adrenergic receptor Protein
UniProt:P07550 Beta-2 adrenergic receptor Protein
MESH:D004837 Epinephrine ChemicalSubstance
MESH:D009638 Norepinephrine ChemicalSubstance
HP:0000822 Hypertension PhenotypicFeature
HP:0001714 Ventricular hypertrophy PhenotypicFeature
MESH:D002312 Cardiomyopathy, Hypertrophic Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Propranolol DECREASES ACTIVITY OF Beta-1 Adrenergic Receptor
Propranolol DECREASES ACTIVITY OF Beta-2 Adrenergic Receptor
Beta-1 Adrenergic Receptor POSITIVELY CORRELATED WITH Epinephrine
Beta-1 Adrenergic Receptor POSITIVELY CORRELATED WITH Norepinephrine
Beta-2 Adrenergic Receptor POSITIVELY CORRELATED WITH Epinephrine
Beta-2 Adrenergic Receptor POSITIVELY CORRELATED WITH Norepinephrine
Epinephrine POSITIVELY CORRELATED WITH Hypertension
Norepinephrine POSITIVELY CORRELATED WITH Hypertension
Hypertension CONTRIBUTES TO Ventricular Hypertrophy
Ventricular Hypertrophy MANIFESTATION OF Cardiomyopathy, Hypertrophic

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