Path ID: DB00570_MESH_D008228_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014747 | vinblastine | Drug |
| UniProt:Q71U36 | Tubulin alpha-1A chain | Protein |
| UniProt:P07437 | Tubulin beta chain | Protein |
| UniProt:Q9UJT1 | Tubulin delta chain | Protein |
| UniProt:P23258 | Tubulin gamma-1 chain | Protein |
| UniProt:Q9UJT0 | Tubulin epsilon chain | Protein |
| GO:1902850 | Microtubule cytoskeleton organization involved in mitosis | BiologicalProcess |
| GO:0140014 | Mitotic nuclear division | BiologicalProcess |
| GO:0008283 | Cell population proliferation | BiologicalProcess |
| MESH:D008228 | Non-Hodgkin’s lymphoma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Vinblastine | DECREASES ACTIVITY OF | Tubulin Alpha-1A Chain |
| Vinblastine | DECREASES ACTIVITY OF | Tubulin Beta Chain |
| Vinblastine | DECREASES ACTIVITY OF | Tubulin Delta Chain |
| Vinblastine | DECREASES ACTIVITY OF | Tubulin Gamma-1 Chain |
| Vinblastine | DECREASES ACTIVITY OF | Tubulin Epsilon Chain |
| Tubulin Alpha-1A Chain | PART OF | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Tubulin Alpha-1A Chain | PART OF | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Tubulin Beta Chain | PART OF | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Tubulin Delta Chain | PART OF | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Tubulin Gamma-1 Chain | PART OF | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Tubulin Epsilon Chain | PART OF | Microtubule Cytoskeleton Organization Involved In Mitosis |
| Microtubule Cytoskeleton Organization Involved In Mitosis | POSITIVELY REGULATES | Mitotic Nuclear Division |
| Mitotic Nuclear Division | POSITIVELY REGULATES | Cell Population Proliferation |
| Cell Population Proliferation | POSITIVELY CORRELATED WITH | Non-Hodgkin’S Lymphoma |
Reference: