Path ID: DB00569_MESH_D020246_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000077425 | fondaparinux | Drug |
| UniProt:P01008 | Antithrombin-III | Protein |
| UniProt:P00742 | Coagulation factor X | Protein |
| GO:0007596 | blood coagulation | BiologicalProcess |
| UBERON:0035552 | deep vein | GrossAnatomicalStructure |
| MESH:D020246 | Venous Thrombosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fondaparinux | POSITIVELY REGULATES | Antithrombin-Iii |
| Antithrombin-Iii | DECREASES ACTIVITY OF | Coagulation Factor X |
| Coagulation Factor X | POSITIVELY CORRELATED WITH | Blood Coagulation |
| Blood Coagulation | LOCATED IN | Deep Vein |
| Deep Vein | LOCATION OF | Venous Thrombosis |
Comment: The disease is also known as Deep venous thrombosis as per DrugCentral. Note that among the original MESH IDs for this drug one of them seems to have been deprecated (MESH:C438268) whereas the other (MESH:C049714) is for a compound where no evidence has been found to be related to fondaparinux.
Reference: