Path ID: DB00561_MESH_D012131_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D004315 | doxapram | Drug |
| UniProt:O14649 | Potassium channel subfamily K member 3 | Protein |
| UniProt:Q9NPC2 | Potassium channel subfamily K member 9 | Protein |
| UBERON:0001629 | carotid body | GrossAnatomicalStructure |
| GO:0003039 | detection of reduced oxygen by carotid body chemoreceptor signaling | BiologicalProcess |
| GO:0003035 | detection of increased carbon dioxide by carotid body chemoreceptor signaling | BiologicalProcess |
| GO:0007585 | respiratory gaseous exchange by respiratory system | BiologicalProcess |
| MESH:D012131 | Decreased respiratory function | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Doxapram | DECREASES ACTIVITY OF | Potassium Channel Subfamily K Member 3 |
| Doxapram | DECREASES ACTIVITY OF | Potassium Channel Subfamily K Member 9 |
| Potassium Channel Subfamily K Member 3 | LOCATED IN | Carotid Body |
| Potassium Channel Subfamily K Member 9 | LOCATED IN | Carotid Body |
| Carotid Body | PARTICIPATES IN | Detection Of Reduced Oxygen By Carotid Body Chemoreceptor Signaling |
| Carotid Body | PARTICIPATES IN | Detection Of Increased Carbon Dioxide By Carotid Body Chemoreceptor Signaling |
| Detection Of Reduced Oxygen By Carotid Body Chemoreceptor Signaling | POSITIVELY CORRELATED WITH | Respiratory Gaseous Exchange By Respiratory System |
| Detection Of Increased Carbon Dioxide By Carotid Body Chemoreceptor Signaling | POSITIVELY CORRELATED WITH | Respiratory Gaseous Exchange By Respiratory System |
| Respiratory Gaseous Exchange By Respiratory System | TREATS | Decreased Respiratory Function |
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