Path ID: DB00552_MESH_D007943_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015649 | pentostatin | Drug |
| UniProt:P00813 | Adenosine deaminase | Protein |
| GO:0046061 | dATP catabolic process | BiologicalProcess |
| GO:0032774 | RNA biosynthetic process | BiologicalProcess |
| CHEBI:16284 | dATP | ChemicalSubstance |
| GO:0006260 | DNA replication | BiologicalProcess |
| GO:0046651 | lymphocyte proliferation | BiologicalProcess |
| MESH:D007943 | Hairy cell leukemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Pentostatin | DECREASES ACTIVITY OF | Adenosine Deaminase |
| Pentostatin | NEGATIVELY REGULATES | Rna Biosynthetic Process |
| Rna Biosynthetic Process | POSITIVELY CORRELATED WITH | Lymphocyte Proliferation |
| Adenosine Deaminase | POSITIVELY REGULATES | Datp Catabolic Process |
| Datp Catabolic Process | DECREASES ABUNDANCE OF | Datp |
| Datp | NEGATIVELY CORRELATED WITH | Dna Replication |
| Dna Replication | POSITIVELY CORRELATED WITH | Lymphocyte Proliferation |
| Lymphocyte Proliferation | POSITIVELY CORRELATED WITH | Hairy Cell Leukemia |
Reference: