Path ID: DB00528_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C060343 | lercanidipine | Drug |
| UniProt:Q06432 | Voltage-dependent calcium channel gamma-1 subunit | Protein |
| GO:0070509 | Transmembrane calcium influx | BiologicalProcess |
| GO:0044557 | smooth muscle relaxation | BiologicalProcess |
| UBERON:0001981 | blood vessel | GrossAnatomicalStructure |
| GO:0008217 | Blood Pressure | BiologicalProcess |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Lercanidipine | DECREASES ACTIVITY OF | Voltage-Dependent Calcium Channel Gamma-1 Subunit |
| Voltage-Dependent Calcium Channel Gamma-1 Subunit | PARTICIPATES IN | Transmembrane Calcium Influx |
| Transmembrane Calcium Influx | CONTRIBUTES TO | Smooth Muscle Relaxation |
| Smooth Muscle Relaxation | LOCATED IN | Blood Vessel |
| Blood Vessel | POSITIVELY REGULATES | Blood Pressure |
| Blood Pressure | POSITIVELY CORRELATED WITH | Hypertensive Disorder |
Reference: