Path ID: DB00527_MESH_D011537_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D003992 | Cinchocaine | Drug |
| UniProt:Q9Y5Y9 | Sodium channel protein type 10 subunit alpha | Protein |
| UniProt:Q14524 | Sodium channel protein type 5 subunit alpha | Protein |
| GO:0005248 | Voltage-gated sodium channel activity | BiologicalProcess |
| GO:0051899 | Membrane depolarization | BiologicalProcess |
| GO:0001508 | Action potential | BiologicalProcess |
| CL:0000197 | Sensory Receptor Cell | Cell |
| MESH:D011537 | Itching of skin | Drug |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cinchocaine | DECREASES ACTIVITY OF | Sodium Channel Protein Type 10 Subunit Alpha |
| Cinchocaine | DECREASES ACTIVITY OF | Sodium Channel Protein Type 5 Subunit Alpha |
| Sodium Channel Protein Type 10 Subunit Alpha | PARTICIPATES IN | Voltage-Gated Sodium Channel Activity |
| Sodium Channel Protein Type 5 Subunit Alpha | PARTICIPATES IN | Voltage-Gated Sodium Channel Activity |
| Voltage-Gated Sodium Channel Activity | POSITIVELY REGULATES | Membrane Depolarization |
| Membrane Depolarization | POSITIVELY REGULATES | Action Potential |
| Action Potential | POSITIVELY REGULATES | Sensory Receptor Cell |
| Sensory Receptor Cell | POSITIVELY CORRELATED WITH | Itching Of Skin |
Reference: