Path ID: DB00525_MESH_D014008_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014047 | Tolnaftate | Drug |
| UniProt:Q92206 | Squalene monooxygenase (Candida albicans) | Protein |
| GO:0006696 | Ergosterol biosynthetic process | BiologicalProcess |
| MESH:D004875 | Ergosterol | ChemicalSubstance |
| GO:0042546 | Cell wall biogenesis | BiologicalProcess |
| taxonomy:4751 | Fungi | OrganismTaxon |
| MESH:D014008 | Tinea pedis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Tolnaftate | DECREASES ACTIVITY OF | Squalene Monooxygenase (Candida Albicans) |
| Squalene Monooxygenase (Candida Albicans) | POSITIVELY REGULATES | Ergosterol Biosynthetic Process |
| Ergosterol Biosynthetic Process | INCREASES ABUNDANCE OF | Ergosterol |
| Ergosterol | PARTICIPATES IN | Cell Wall Biogenesis |
| Cell Wall Biogenesis | OCCURS IN | Fungi |
| Fungi | CAUSES | Tinea Pedis |
Reference: