Path ID: DB00517_MESH_D013276_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C100237 | octatropine methylbromide | Drug |
| UniProt:P11229 | Muscarinic acetylcholine receptor M1 | Protein |
| UniProt:P08172 | Muscarinic acetylcholine receptor M2 | Protein |
| UniProt:P20309 | Muscarinic acetylcholine receptor M3 | Protein |
| GO:0095500 | acetylcholine receptor signaling pathway | BiologicalProcess |
| MESH:D000109 | Acetylcholine | ChemicalSubstance |
| GO:0001696 | gastric acid secretion | BiologicalProcess |
| MESH:D010437 | Peptic Ulcer | Disease |
| UBERON:0000945 | stomach | GrossAnatomicalStructure |
| MESH:D013276 | Stomach Ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Octatropine Methylbromide | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M1 |
| Octatropine Methylbromide | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M2 |
| Octatropine Methylbromide | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M3 |
| Muscarinic Acetylcholine Receptor M1 | POSITIVELY REGULATES | Acetylcholine Receptor Signaling Pathway |
| Muscarinic Acetylcholine Receptor M2 | POSITIVELY REGULATES | Acetylcholine Receptor Signaling Pathway |
| Muscarinic Acetylcholine Receptor M3 | POSITIVELY REGULATES | Acetylcholine Receptor Signaling Pathway |
| Acetylcholine Receptor Signaling Pathway | POSITIVELY CORRELATED WITH | Acetylcholine |
| Acetylcholine | POSITIVELY CORRELATED WITH | Gastric Acid Secretion |
| Gastric Acid Secretion | CONTRIBUTES TO | Peptic Ulcer |
| Peptic Ulcer | LOCATED IN | Stomach |
| Stomach | LOCATION OF | Stomach Ulcer |
Reference: