Path ID: DB00505_MESH_D010437_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C005386 | Tridihexethyl | Drug |
| UniProt:P20309 | Muscarinic acetylcholine receptor M3 | Protein |
| GO:0001699 | Acetylcholine-induced gastric acid secretion | BiologicalProcess |
| MESH:D005744 | Gastric acid | ChemicalSubstance |
| InterPro:IPR034162 | Pepsin catalytic domain | GeneFamily |
| MESH:D010437 | Peptic ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Tridihexethyl | DECREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor M3 |
| Muscarinic Acetylcholine Receptor M3 | PARTICIPATES IN | Acetylcholine-Induced Gastric Acid Secretion |
| Acetylcholine-Induced Gastric Acid Secretion | INCREASES ABUNDANCE OF | Gastric Acid |
| Gastric Acid | POSITIVELY REGULATES | Pepsin Catalytic Domain |
| Pepsin Catalytic Domain | POSITIVELY CORRELATED WITH | Peptic Ulcer |
Comment: Withdrawn. Tridihexethyl is no longer available in the US market.
Reference: