Path ID: DB00501_MESH_D004381_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002927 | Cimetidine | Drug |
| UniProt:P25021 | Histamine H2 receptor | Protein |
| GO:0001696 | gastric acid secretion | BiologicalProcess |
| MESH:D005744 | Gastric Acid | ChemicalSubstance |
| MESH:D010437 | Peptic Ulcer | Disease |
| UBERON:0002114 | duodenum | GrossAnatomicalStructure |
| MESH:D004381 | Duodenal Ulcer | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cimetidine | DECREASES ACTIVITY OF | Histamine H2 Receptor |
| Histamine H2 Receptor | POSITIVELY REGULATES | Gastric Acid Secretion |
| Gastric Acid Secretion | INCREASES ABUNDANCE OF | Gastric Acid |
| Gastric Acid | CONTRIBUTES TO | Peptic Ulcer |
| Peptic Ulcer | LOCATED IN | Duodenum |
| Duodenum | LOCATION OF | Duodenal Ulcer |
Reference: