Path ID: DB00499_MESH_D011471_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D005485 | flutamide | Drug |
| UniProt:P10275 | Androgen receptor | Protein |
| GO:0030521 | androgen receptor signaling pathway | BiologicalProcess |
| GO:0006351 | gene transcription | BiologicalProcess |
| GO:0008283 | cell population proliferation | BiologicalProcess |
| CL:0001063 | tumor cell | Cell |
| MESH:D011471 | Malignant tumor of prostate | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Flutamide | DECREASES ACTIVITY OF | Androgen Receptor |
| Androgen Receptor | PARTICIPATES IN | Androgen Receptor Signaling Pathway |
| Androgen Receptor Signaling Pathway | POSITIVELY REGULATES | Gene Transcription |
| Gene Transcription | PRECEDES | Cell Population Proliferation |
| Cell Population Proliferation | POSITIVELY CORRELATED WITH | Tumor Cell |
| Tumor Cell | POSITIVELY CORRELATED WITH | Malignant Tumor Of Prostate |
Reference: