Path ID: DB00472_MESH_D001714_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D005473 | fluoxetine | Drug |
| UniProt:P31645 | Sodium-dependent serotonin transporter | Protein |
| GO:0051610 | Serotonin uptake | BiologicalProcess |
| MESH:D012701 | Serotonin | ChemicalSubstance |
| GO:0060096 | Serotonin secretion, neurotransmission | BiologicalProcess |
| MESH:D001714 | Bipolar affective disorder, current episode depression | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Fluoxetine | DECREASES ACTIVITY OF | Sodium-Dependent Serotonin Transporter |
| Sodium-Dependent Serotonin Transporter | POSITIVELY REGULATES | Serotonin Uptake |
| Serotonin Uptake | DECREASES ABUNDANCE OF | Serotonin |
| Serotonin | POSITIVELY CORRELATED WITH | Serotonin Secretion, Neurotransmission |
| Serotonin Secretion, Neurotransmission | NEGATIVELY REGULATES | Bipolar Affective Disorder, Current Episode Depression |
Reference: