Path ID: DB00432_MESH_D016849_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014271 | Trifluridine | Drug |
| GO:0039693 | Viral DNA genome replication | BiologicalProcess |
| taxonomy:10298 | Human alphaherpesvirus 1 | OrganismTaxon |
| MESH:D016849 | Herpes simplex keratitis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Trifluridine | NEGATIVELY REGULATES | Viral Dna Genome Replication |
| Viral Dna Genome Replication | IN TAXON | Human Alphaherpesvirus 1 |
| Human Alphaherpesvirus 1 | CAUSES | Herpes Simplex Keratitis |
Comment: The mechanism of action of trifluridine as an antiviral agent has not been fully elucidated, but appears to involve the inhibition of viral replication.
Reference: