Path ID: DB00429_MESH_D006473_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C062843 | carboprost tromethamine | Drug |
| UniProt:P34995 | Prostaglandin E2 receptor EP1 subtype | Protein |
| GO:0070471 | uterine smooth muscle contraction | BiologicalProcess |
| GO:0042310 | vasoconstriction | BiologicalProcess |
| MESH:D006473 | Postpartum Hemorrhage | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Carboprost Tromethamine | INCREASES ACTIVITY OF | Prostaglandin E2 Receptor Ep1 Subtype |
| Prostaglandin E2 Receptor Ep1 Subtype | POSITIVELY REGULATES | Uterine Smooth Muscle Contraction |
| Uterine Smooth Muscle Contraction | POSITIVELY CORRELATED WITH | Vasoconstriction |
| Vasoconstriction | NEGATIVELY CORRELATED WITH | Postpartum Hemorrhage |
Reference: