Path ID: DB00411_MESH_D005902_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002217 | carbachol | Drug |
| InterPro:IPR000995 | Muscarinic acetylcholine receptor family | GeneFamily |
| reactome:R-HSA-390648 | Muscarinic acetylcholine receptors | Pathway |
| GO:0006939 | smooth muscle contraction | BiologicalProcess |
| HP:0000616 | Miosis | PhenotypicFeature |
| HP:0007906 | Ocular Hypertension | PhenotypicFeature |
| MESH:D005902 | Open-angle glaucoma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Carbachol | INCREASES ACTIVITY OF | Muscarinic Acetylcholine Receptor Family |
| Muscarinic Acetylcholine Receptor Family | PARTICIPATES IN | Muscarinic Acetylcholine Receptors |
| Muscarinic Acetylcholine Receptors | POSITIVELY CORRELATED WITH | Smooth Muscle Contraction |
| Smooth Muscle Contraction | CORRELATED WITH | Miosis |
| Miosis | NEGATIVELY CORRELATED WITH | Ocular Hypertension |
| Ocular Hypertension | POSITIVELY CORRELATED WITH | Open-Angle Glaucoma |
Reference: