Path ID: DB00393_MESH_D013345_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009553 | Nimodipine | Drug |
| InterPro:IPR031649 | Voltage-dependent L-type calcium channel, IQ-associated domain | GeneFamily |
| GO:0070509 | Calcium ion import | BiologicalProcess |
| GO:0006939 | Smooth muscle contraction | BiologicalProcess |
| GO:0042310 | Vasoconstriction | BiologicalProcess |
| HP:0025637 | Vasospasm | PhenotypicFeature |
| MESH:D013345 | Subarachnoid intracranial hemorrhage | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Nimodipine | DECREASES ACTIVITY OF | Voltage-Dependent L-Type Calcium Channel, Iq-Associated Domain |
| Voltage-Dependent L-Type Calcium Channel, Iq-Associated Domain | POSITIVELY REGULATES | Calcium Ion Import |
| Calcium Ion Import | POSITIVELY REGULATES | Smooth Muscle Contraction |
| Smooth Muscle Contraction | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | POSITIVELY CORRELATED WITH | Vasospasm |
| Vasospasm | POSITIVELY CORRELATED WITH | Subarachnoid Intracranial Hemorrhage |
Reference: