Path ID: DB00389_MESH_D006111_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002231 | carbimazole | Drug |
| CHEBI:50673 | methimazole | ChemicalSubstance |
| UniProt:P07202 | Thyroid peroxidase | Protein |
| GO:0006590 | thyroid hormone generation | BiologicalProcess |
| HP:0000836 | Hyperthyroidism | PhenotypicFeature |
| MESH:D006111 | Graves’ disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Carbimazole | HAS METABOLITE | Methimazole |
| Methimazole | DECREASES ACTIVITY OF | Thyroid Peroxidase |
| Thyroid Peroxidase | PARTICIPATES IN | Thyroid Hormone Generation |
| Thyroid Hormone Generation | POSITIVELY CORRELATED WITH | Hyperthyroidism |
| Hyperthyroidism | MANIFESTATION OF | Graves’ Disease |
Reference: