Path ID: DB00384_MESH_D006973_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014223 | triamterene | Drug |
| Pfam:PF00858 | Amiloride-sensitive sodium channel | GeneFamily |
| GO:0070294 | renal sodium ion absorption | BiologicalProcess |
| GO:0003092 | renal water retention | BiologicalProcess |
| HP:0011105 | Hypervolemia | PhenotypicFeature |
| MESH:D006973 | Hypertensive disorder | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Triamterene | NEGATIVELY REGULATES | Amiloride-Sensitive Sodium Channel |
| Amiloride-Sensitive Sodium Channel | POSITIVELY REGULATES | Renal Sodium Ion Absorption |
| Renal Sodium Ion Absorption | POSITIVELY CORRELATED WITH | Renal Water Retention |
| Renal Water Retention | POSITIVELY CORRELATED WITH | Hypervolemia |
| Hypervolemia | POSITIVELY CORRELATED WITH | Hypertensive Disorder |
Reference: