Path ID: DB00382_MESH_D000544_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D013619 | Tacrine | Drug |
| UniProt:P22303 | Cholinesterase | Protein |
| MESH:D000109 | Acetylcholine | ChemicalSubstance |
| MESH:D000544 | Alzheimer’s disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Tacrine | DECREASES ACTIVITY OF | Cholinesterase |
| Cholinesterase | INCREASES ABUNDANCE OF | Acetylcholine |
| Acetylcholine | AMELIORATES | Alzheimer’S Disease |
Comment: Tacrine has been discontinued for the United States market.
Reference: