Path ID: DB00375_MESH_D006937_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D003084 | Colestipol | Drug |
| MESH:D001647 | Bile Acids and Salts | ChemicalSubstance |
| MESH:D002784 | Cholesterol | ChemicalSubstance |
| UniProt:P01130 | Low-density lipoprotein receptor | Protein |
| GO:0034383 | Low-density lipoprotein particle clearance | BiologicalProcess |
| MESH:D008077 | Lipoproteins, LDL | ChemicalSubstance |
| MESH:D006937 | Hypercholesterolemia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Colestipol | DECREASES ABUNDANCE OF | Bile Acids And Salts |
| Bile Acids And Salts | DERIVES FROM | Cholesterol |
| Cholesterol | POSITIVELY CORRELATED WITH | Hypercholesterolemia |
| Colestipol | INCREASES ACTIVITY OF | Low-Density Lipoprotein Receptor |
| Low-Density Lipoprotein Receptor | POSITIVELY REGULATES | Low-Density Lipoprotein Particle Clearance |
| Low-Density Lipoprotein Particle Clearance | DECREASES ABUNDANCE OF | Lipoproteins, Ldl |
| Lipoproteins, Ldl | POSITIVELY CORRELATED WITH | Hypercholesterolemia |
Reference: