Path ID: DB00368_MESH_D011656_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D009638 | norepinephrine | Drug |
| UniProt:P07550 | Beta-2 adrenergic receptor | Protein |
| GO:0044557 | relaxation of smooth muscle | BiologicalProcess |
| HP:0002094 | Dyspnea | PhenotypicFeature |
| HP:0006536 | Airway obstruction | PhenotypicFeature |
| HP:0030828 | Wheezing | PhenotypicFeature |
| HP:0012735 | Cough | PhenotypicFeature |
| MESH:D011656 | Pulmonary emphysema | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Norepinephrine | POSITIVELY REGULATES | Beta-2 Adrenergic Receptor |
| Beta-2 Adrenergic Receptor | POSITIVELY REGULATES | Relaxation Of Smooth Muscle |
| Relaxation Of Smooth Muscle | NEGATIVELY CORRELATED WITH | Wheezing |
| Relaxation Of Smooth Muscle | NEGATIVELY CORRELATED WITH | Dyspnea |
| Relaxation Of Smooth Muscle | NEGATIVELY CORRELATED WITH | Airway Obstruction |
| Relaxation Of Smooth Muscle | NEGATIVELY CORRELATED WITH | Cough |
| Dyspnea | MANIFESTATION OF | Pulmonary Emphysema |
| Airway Obstruction | MANIFESTATION OF | Pulmonary Emphysema |
| Cough | MANIFESTATION OF | Pulmonary Emphysema |
| Wheezing | MANIFESTATION OF | Pulmonary Emphysema |
Reference: