Path ID: DB00364_MESH_D004381_1

Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D013392 | sucralfate | Drug |
| UniProt:P0DJD9 | Pepsin A-5 | Protein |
| GO:0032310 | prostaglandin secretion | BiologicalProcess |
| GO:0001516 | prostaglandin biosynthetic process | BiologicalProcess |
| GO:0070254 | mucus secretion | BiologicalProcess |
| MESH:D001639 | Bicarbonates | ChemicalSubstance |
| CHEBI:22868 | bile salt | ChemicalSubstance |
| MESH:D004381 | Duodenal ulcer disease | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Sucralfate | DECREASES ACTIVITY OF | Pepsin A-5 |
| Pepsin A-5 | POSITIVELY CORRELATED WITH | Duodenal Ulcer Disease |
| Sucralfate | DECREASES ABUNDANCE OF | Bile Salt |
| Bile Salt | POSITIVELY CORRELATED WITH | Duodenal Ulcer Disease |
| Sucralfate | POSITIVELY REGULATES | Prostaglandin Secretion |
| Sucralfate | POSITIVELY REGULATES | Prostaglandin Biosynthetic Process |
| Sucralfate | POSITIVELY REGULATES | Mucus Secretion |
| Sucralfate | INCREASES ABUNDANCE OF | Bicarbonates |
| Bicarbonates | NEGATIVELY CORRELATED WITH | Duodenal Ulcer Disease |
| Prostaglandin Secretion | NEGATIVELY CORRELATED WITH | Duodenal Ulcer Disease |
| Prostaglandin Biosynthetic Process | NEGATIVELY CORRELATED WITH | Duodenal Ulcer Disease |
| Mucus Secretion | NEGATIVELY CORRELATED WITH | Duodenal Ulcer Disease |
Reference: