Path ID: DB00358_MESH_D016780_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D015767 | Mefloquine | Drug |
| GO:0005840 | Ribosome | CellularComponent |
| GO:0006412 | Translation | BiologicalProcess |
| taxonomy:5855 | Plasmodium vivax | OrganismTaxon |
| MESH:D016780 | Vivax malaria | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Mefloquine | DECREASES ACTIVITY OF | Ribosome |
| Ribosome | POSITIVELY REGULATES | Translation |
| Translation | IN TAXON | Plasmodium Vivax |
| Plasmodium Vivax | CAUSES | Vivax Malaria |
Comment: The mechanism of action of mefloquine is not completely understood. Some studies suggest that mefloquine specifically targets the 80S ribosome.
Reference: