Path ID: DB00357_MESH_D001943_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000616 | aminoglutethimide | Drug |
| UniProt:P11511 | aromatase | Protein |
| MESH:D004967 | estrogen | ChemicalSubstance |
| GO:0008283 | Cell proliferation | BiologicalProcess |
| MESH:D001943 | Secondary malignant neoplasm of female breast | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Aminoglutethimide | DECREASES ACTIVITY OF | Aromatase |
| Aromatase | PRODUCES | Estrogen |
| Estrogen | POSITIVELY REGULATES | Cell Proliferation |
| Cell Proliferation | POSITIVELY CORRELATED WITH | Secondary Malignant Neoplasm Of Female Breast |
Reference: