Path ID: DB00335_MESH_D009203_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D001262 | Atenolol | Drug |
| UniProt:P08588 | Beta-1 adrenergic receptor | Protein |
| UniProt:P00797 | Renin | Protein |
| GO:0042310 | Vasoconstriction | BiologicalProcess |
| HP:0032263 | Increased blood pressure | PhenotypicFeature |
| HP:0033401 | Tissue ischemia | PhenotypicFeature |
| UBERON:0000948 | Heart | GrossAnatomicalStructure |
| MESH:D009203 | Myocardial infarction | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Atenolol | DECREASES ACTIVITY OF | Beta-1 Adrenergic Receptor |
| Beta-1 Adrenergic Receptor | POSITIVELY REGULATES | Renin |
| Beta-1 Adrenergic Receptor | POSITIVELY REGULATES | Vasoconstriction |
| Renin | POSITIVELY REGULATES | Vasoconstriction |
| Vasoconstriction | POSITIVELY CORRELATED WITH | Increased Blood Pressure |
| Increased Blood Pressure | AFFECTS RISK FOR | Myocardial Infarction |
| Vasoconstriction | AFFECTS RISK FOR | Tissue Ischemia |
| Tissue Ischemia | LOCATED IN | Heart |
| Heart | LOCATION OF | Myocardial Infarction |
Reference: