Path ID: DB00330_MESH_D014397_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D004977 | Ethambutol | Drug |
| UniProt:P9WNL5 | Probable arabinosyltransferase C | Protein |
| UniProt:P9WNL7 | Probable arabinosyltransferase B | Protein |
| UniProt:P9WNL9 | Probable arabinosyltransferase A | Protein |
| GO:0071766 | Actinobacterium-type cell wall biogenesis | BiologicalProcess |
| GO:0051301 | Cell division | BiologicalProcess |
| taxonomy:1773 | Mycobacterium tuberculosis | OrganismTaxon |
| MESH:D014397 | Pulmonary tuberculosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Ethambutol | DECREASES ACTIVITY OF | Probable Arabinosyltransferase C |
| Ethambutol | DECREASES ACTIVITY OF | Probable Arabinosyltransferase B |
| Ethambutol | DECREASES ACTIVITY OF | Probable Arabinosyltransferase A |
| Probable Arabinosyltransferase C | POSITIVELY REGULATES | Actinobacterium-Type Cell Wall Biogenesis |
| Probable Arabinosyltransferase B | POSITIVELY REGULATES | Actinobacterium-Type Cell Wall Biogenesis |
| Probable Arabinosyltransferase A | POSITIVELY REGULATES | Actinobacterium-Type Cell Wall Biogenesis |
| Actinobacterium-Type Cell Wall Biogenesis | POSITIVELY CORRELATED WITH | Cell Division |
| Cell Division | IN TAXON | Mycobacterium Tuberculosis |
| Mycobacterium Tuberculosis | CAUSES | Pulmonary Tuberculosis |
Comment: Ethambutol is indicated in combination with other anti-tuberculosis drugs in the treatment of pulmonary tuberculosis
Reference: