Path ID: DB00316_MESH_D018771_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000082 | Acetaminophen | Drug |
| UniProt:P23219 | Prostaglandin G/H synthase 1 | Protein |
| UniProt:P35354 | Prostaglandin G/H synthase 2 | Protein |
| UniProt:Q15185 | Prostaglandin E synthase 3 | Protein |
| GO:0001516 | prostaglandin biosynthetic process | BiologicalProcess |
| MESH:D011453 | Prostaglandins | ChemicalSubstance |
| MESH:D018771 | Arthralgia | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Acetaminophen | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 1 |
| Acetaminophen | DECREASES ACTIVITY OF | Prostaglandin G/H Synthase 2 |
| Acetaminophen | DECREASES ACTIVITY OF | Prostaglandin E Synthase 3 |
| Prostaglandin G/H Synthase 1 | POSITIVELY REGULATES | Prostaglandin Biosynthetic Process |
| Prostaglandin G/H Synthase 2 | POSITIVELY REGULATES | Prostaglandin Biosynthetic Process |
| Prostaglandin E Synthase 3 | POSITIVELY REGULATES | Prostaglandin Biosynthetic Process |
| Prostaglandin Biosynthetic Process | INCREASES ABUNDANCE OF | Prostaglandins |
| Prostaglandins | POSITIVELY CORRELATED WITH | Arthralgia |
Reference: