Path ID: DB00313_MESH_D008881_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D014635 | valproic acid | Drug |
| UniProt:O14975 | microsomal long-chain fatty acyl-CoA synthetase | Protein |
| UBERON:0000955 | brain | GrossAnatomicalStructure |
| MESH:C026563 | Arachidonoyl-CoA | ChemicalSubstance |
| reactome:R-HSA-2162123 | inflammatory prostaglandins production | Pathway |
| MESH:D008881 | migraine | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Valproic Acid | DECREASES ACTIVITY OF | Microsomal Long-Chain Fatty Acyl-Coa Synthetase |
| Microsomal Long-Chain Fatty Acyl-Coa Synthetase | LOCATED IN | Brain |
| Brain | DECREASES ABUNDANCE OF | Arachidonoyl-Coa |
| Arachidonoyl-Coa | PARTICIPATES IN | Inflammatory Prostaglandins Production |
| Inflammatory Prostaglandins Production | TREATS | Migraine |
Reference: