Path ID: DB00313_MESH_D004832_1

db00313-mesh-d004832-1

Concepts

Identifier Name Type
MESH:D014635 Valproic Acid Drug
UniProt:P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Protein
UniProt:Q9UKV0 Histone deacetylase 9 Protein
GO:0009450 gamma-aminobutyric acid catabolic process BiologicalProcess
GO:0016575 histone deacetylation BiologicalProcess
GO:0010629 negative regulation of gene expression BiologicalProcess
MESH:D004832 Epilepsy, Absence Disease

Relationships

NOTE: predicates are annotated in Biolink Model (v1.3.0)

Subject Predicate Object
Valproic Acid DECREASES ACTIVITY OF Succinate-Semialdehyde Dehydrogenase, Mitochondrial
Valproic Acid DECREASES ACTIVITY OF Histone Deacetylase 9
Succinate-Semialdehyde Dehydrogenase, Mitochondrial POSITIVELY REGULATES Gamma-Aminobutyric Acid Catabolic Process
Histone Deacetylase 9 POSITIVELY REGULATES Histone Deacetylation
Histone Deacetylation CORRELATED WITH Negative Regulation Of Gene Expression
Gamma-Aminobutyric Acid Catabolic Process POSITIVELY CORRELATED WITH Epilepsy, Absence
Negative Regulation Of Gene Expression CONTRIBUTES TO Epilepsy, Absence

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