Path ID: DB00307_MESH_D016410_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C095105 | Bexarotene | Drug |
| UniProt:P19793 | Retinoic acid receptor RXR-alpha | Protein |
| UniProt:P28702 | Retinoic acid receptor RXR-beta | Protein |
| UniProt:P48443 | Retinoic acid receptor RXR-gamma | Protein |
| HP:0031379 | Abnormal T cell proliferation | PhenotypicFeature |
| MESH:D016410 | Primary cutaneous T-cell lymphoma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Bexarotene | INCREASES ACTIVITY OF | Retinoic Acid Receptor Rxr-Alpha |
| Bexarotene | INCREASES ACTIVITY OF | Retinoic Acid Receptor Rxr-Beta |
| Bexarotene | INCREASES ACTIVITY OF | Retinoic Acid Receptor Rxr-Gamma |
| Retinoic Acid Receptor Rxr-Alpha | NEGATIVELY REGULATES | Abnormal T Cell Proliferation |
| Retinoic Acid Receptor Rxr-Beta | NEGATIVELY REGULATES | Abnormal T Cell Proliferation |
| Retinoic Acid Receptor Rxr-Gamma | NEGATIVELY REGULATES | Abnormal T Cell Proliferation |
| Abnormal T Cell Proliferation | POSITIVELY CORRELATED WITH | Primary Cutaneous T-Cell Lymphoma |
Reference: