Path ID: DB00299_MESH_D006560_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:C053539 | penciclovir | Drug |
| MESH:C092310 | penciclovir triphosphate | ChemicalSubstance |
| UniProt:P04293 | DNA polymerase catalytic subunit | Protein |
| GO:0039693 | viral DNA genome replication | BiologicalProcess |
| taxonomy:10298 | Human alphaherpesvirus 1 | OrganismTaxon |
| MESH:D006560 | Herpes Labialis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Penciclovir | HAS METABOLITE | Penciclovir Triphosphate |
| Penciclovir Triphosphate | DECREASES ACTIVITY OF | Dna Polymerase Catalytic Subunit |
| Dna Polymerase Catalytic Subunit | POSITIVELY REGULATES | Viral Dna Genome Replication |
| Viral Dna Genome Replication | IN TAXON | Human Alphaherpesvirus 1 |
| Human Alphaherpesvirus 1 | CAUSES | Herpes Labialis |
Reference: