Path ID: DB00262_MESH_D008228_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D002330 | Carmustine | Drug |
| UniProt:P00390 | Glutathione reductase, mitochondrial | Protein |
| MESH:D004247 | DNA | ChemicalSubstance |
| MESH:D012313 | RNA | ChemicalSubstance |
| GO:0034599 | Cellular response to oxidative stress | BiologicalProcess |
| GO:0006260 | DNA replication | BiologicalProcess |
| GO:0006412 | Translation | BiologicalProcess |
| GO:0008219 | Cell death | BiologicalProcess |
| MESH:D008228 | Non-Hodgkin’s lymphoma | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Carmustine | DECREASES ACTIVITY OF | Glutathione Reductase, Mitochondrial |
| Carmustine | DISRUPTS | Dna |
| Carmustine | DISRUPTS | Rna |
| Glutathione Reductase, Mitochondrial | PARTICIPATES IN | Cellular Response To Oxidative Stress |
| Dna | PARTICIPATES IN | Dna Replication |
| Rna | PARTICIPATES IN | Translation |
| Cellular Response To Oxidative Stress | CAPABLE OF | Cell Death |
| Dna Replication | OCCURS IN | Non-Hodgkin’S Lymphoma |
| Translation | OCCURS IN | Non-Hodgkin’S Lymphoma |
| Cell Death | NEGATIVELY CORRELATED WITH | Non-Hodgkin’S Lymphoma |
Reference: