Path ID: DB00260_MESH_D014397_1
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D003523 | Cycloserine | Drug |
| UniProt:P9WP31 | D-alanine–D-alanine ligase (Mycobacterium tuberculosis) | Protein |
| UniProt:P9WQA9 | Alanine racemase (Mycobacterium tuberculosis) | Protein |
| GO:0009252 | Peptidoglycan biosynthetic process | BiologicalProcess |
| GO:0009273 | Peptidoglycan-based cell wall biogenesis | BiologicalProcess |
| GO:0051301 | Cell division | BiologicalProcess |
| taxonomy:1773 | Mycobacterium tuberculosis | OrganismTaxon |
| MESH:D014397 | Pulmonary tuberculosis | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Cycloserine | DECREASES ACTIVITY OF | D-Alanine–D-Alanine Ligase (Mycobacterium Tuberculosis) |
| Cycloserine | DECREASES ACTIVITY OF | Alanine Racemase (Mycobacterium Tuberculosis) |
| D-Alanine–D-Alanine Ligase (Mycobacterium Tuberculosis) | POSITIVELY REGULATES | Peptidoglycan Biosynthetic Process |
| Alanine Racemase (Mycobacterium Tuberculosis) | POSITIVELY REGULATES | Peptidoglycan Biosynthetic Process |
| Peptidoglycan Biosynthetic Process | POSITIVELY REGULATES | Peptidoglycan-Based Cell Wall Biogenesis |
| Peptidoglycan-Based Cell Wall Biogenesis | POSITIVELY CORRELATED WITH | Cell Division |
| Cell Division | OCCURS IN | Mycobacterium Tuberculosis |
| Mycobacterium Tuberculosis | CAUSES | Pulmonary Tuberculosis |
Reference: