Path ID: DB00257_MESH_D000152_2
Concepts
| Identifier | Name | Type |
|---|---|---|
| MESH:D000068816 | Adapalene | Drug |
| UniProt:O60603 | Toll-like receptor 2 | Protein |
| UniProt:P05412 | Transcription factor AP-1 | Protein |
| GO:0006954 | inflammatory response | BiologicalProcess |
| GO:0006954 | inflammatory response | BiologicalProcess |
| taxonomy:1747 | Cutibacterium acnes | OrganismTaxon |
| MESH:D000152 | Acne vulgaris | Disease |
Relationships
NOTE: predicates are annotated in Biolink Model (v1.3.0)
| Subject | Predicate | Object |
|---|---|---|
| Adapalene | NEGATIVELY REGULATES | Toll-Like Receptor 2 |
| Toll-Like Receptor 2 | POSITIVELY REGULATES | Transcription Factor Ap-1 |
| Transcription Factor Ap-1 | POSITIVELY CORRELATED WITH | Inflammatory Response |
| Inflammatory Response | CAUSED BY | Cutibacterium Acnes |
| Cutibacterium Acnes | POSITIVELY CORRELATED WITH | Acne Vulgaris |
Reference: